Overview of Bioinformatics Repositories: Centralizing Biological Data for Scientific Advancement

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Tags: repository, database

A bioinformatics depository is a database or repository that stores various types of biological information, such as genomic sequences, protein structures, transcriptomics, proteomics, and metabolomics data. These repositories facilitate the sharing of data among researchers, enabling the scientific community to access, analyze, and build upon existing knowledge.

Some well-known bioinformatics depositories include:

  • National Center for Biotechnology Information (NCBI): A comprehensive database that provides access to a wide range of biological information, including genomic, transcriptomic, and proteomic data.

  • European Bioinformatics Institute (EMBL-EBI): A hub for bioinformatics research and services, offering access to various databases, such as Ensembl, UniProt, and ArrayExpress.

  • DNA Data Bank of Japan (DDBJ): A database that collects and provides nucleotide sequence data, as well as tools for data analysis.

  • Protein Data Bank (PDB): A database that stores 3D protein structures determined by experimental methods like X-ray crystallography, NMR spectroscopy, and cryo-electron microscopy.

  • Gene Expression Omnibus (GEO): A public repository that archives and freely distributes high-throughput gene expression and other functional genomics data sets.

  • The Sequence Read Archive (SRA): A database that stores raw sequencing data from various platforms, such as Illumina, PacBio, and Oxford Nanopore.

These depositories play a crucial role in advancing biological research by providing scientists with a centralized platform to access and share valuable data.

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