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梅尔克细胞病毒小抗原通过类型I干扰素信号传导而促进免疫逃逸

Author: gene_x

Abstract: 详细解释:梅尔克细胞多瘤病毒(Merkel cell polyomavirus,MCPyV)的小肿瘤抗原(small tumor antigen,sT)是该病毒的一个重要组分,通过干扰类型I干扰素(type I interferon)信号传导来促进免疫逃逸。 类型I干扰素是免疫系统中的一类重要信号分子,对抗病毒感染和肿瘤发展起着关键作用。然而,MCPyV的小肿瘤抗原通过干扰类型I干扰素信号的正常

Calculate AT content of the flanking regions of peaks

Author: gene_x

Abstract: #!/usr/bin/env python3 #python3 plot_peaks.py peaks.bed /home/jhuang/REFs/gencode.v43.annotation.gtf.db /ref/Homo_sapiens/UCSC/hg38/Sequence/WholeGenomeFasta/genome.fa #~/Tools/csv2xls-0.4/csv_to_x

Tools for SNP Visualization

Author: gene_x

Abstract: For SNP visualization in Python, we can consider using the following packages: * Matplotlib: Matplotlib is a popular plotting library in Python that can be used to create various types of visualizati

RNAseq processing (1457)

Author: gene_x

Abstract: 1. construct DESeqDataSet from Matrix library("AnnotationDbi") library("clusterProfiler") library("ReactomePA") library("org.Hs.eg.db") library(DESeq2) library(gplots) library(ggplot2)

Exploring Integrative Analysis of Multi-Omics Data from Public Repositories

Author: gene_x

Abstract: 1. Integration and analysis of multi-omics data: Explore the integration of different types of omics data (e.g., genomics, transcriptomics, proteomics) from public repositories to uncover novel biolog

Defining and Categorizing Promoter Types Based on the 'GRGGC' Motif Frequency and Distance to TSS

Author: gene_x

Abstract: 1. generate_promter_sequences #!/usr/bin/env python3 #./1_generate_promoter_sequences.py gencode.v43.annotation.gtf.db import gffutils from pyfaidx import Fasta import argparse from Bio i

Antibodies and cell lines that are commonly used in research

Author: gene_x

Abstract: >http://genome.ucsc.edu/cgi-bin/hgTrackUi?db=hg19&g=wgEncodeBroadHistone Antibody: - CBP (SC-369) - H3K4me1 - H3K4me2 - H3K4me3 - H3K9ac - H3K9me1 - H3K9me3 - H3K27ac - H3K27me3 - H3K36me3 - H3K79me

Gonna、wanna、gotta

Author: huang

Abstract: 1. Gonna 將會 Gonna 是 (be) going to 的非正式用法,表示「某人將會/將要做某事」的意思,常見於口語對話或是流行歌曲中,是一種比較輕鬆的表達方式,其句型為「主詞+be 動詞+gonna+原形動詞」。 A: Dylan, do you have any plans for Chinese New Year ? A:Dylan,你農曆年有沒有什麼計畫? B: Oh

Identifying the Nearest Genomic Peaks within Defined Regions

Author: gene_x

Abstract: To find the closest peaks in the genome regions defined by a bed file, you can use a tool like BEDTools. BEDTools provides a function `closest` which allows you to find the closest feature in a second

LiftOver: An Essential Utility for the Conversion of Genomic Coordinates

Author: gene_x

Abstract: If you have genomic coordinates (like gene positions, SNP positions etc) in hg19 and want to convert them to hg38, you'd use what's known as a "liftover". The UCSC Genome Browser provides a tool speci


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