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Analyzing Caspase 1 Activity: A Study Using Mouse Antibody Detection and GFP Tagging

Author: gene_x

Abstract: [![how_to_measure_signal_caspase1](/static/how_to_measure_signal_caspase1.png "how_to_measure_signal_caspase1")](/static/how_to_measure_signal_caspase1.png "how_to_measure_signal_caspase1") When stud

Inflammasome

Author: gene_x

Abstract: > https://www.nature.com/articles/s41421-020-0167-x 炎症小体是由传感蛋白、炎症性半胱天冬酶以及在某些情况下连接这两者的适配蛋白组成的细胞质多蛋白复合体。它们能够响应多种内源性和外源性刺激,激活经典的半胱天冬酶-1、非经典的半胱天冬酶-11(或人类中的半胱天冬酶-4和半胱天冬酶-5)或半胱天冬酶-8。这一过程导致IL-1β和IL-18的分泌以及凋

Functions of Polyomavirus sT and LT Proteins

Author: gene_x

Abstract: 1. 多瘤病毒的小T蛋白(sT)主要在调节宿主细胞的生长和代谢方面发挥作用。尽管sT的具体功能可能因不同的多瘤病毒类型而异,但它通常与以下几个方面相关: - 细胞周期控制:sT蛋白可以干扰宿主细胞的正常细胞周期进程,促进细胞进入DNA复制阶段,从而有助于病毒DNA的复制。 - 信号传导:sT蛋白能够影响细胞内的信号传递路径,包括激活某些蛋白激酶,改变细胞内环境,促进病毒复制和细

Tarif RRIG (Riester-Rente)

Author: gene_x

Abstract: I. Grundbegriffe und Erläuterungen Diese fondsgebundene Rentenversicherung mit Garantieleistungen (Riester-Rente) hat die Tarifbezeichnung RRIG. Mit den nachfolgenden Grundbegriff

Back-splice junctions

Author: gene_x

Abstract: > To Be or Not to Be: Circular RNAs or mRNAs From Circular DNAs? > https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2019.00940/full 回剪接结 (Back-splice junctions) 是环状RNA (circRNAs)

基因编辑技术的比较

Author: gene_x

Abstract: siRNA沉默: siRNA沉默是一种利用小干扰RNA(siRNA)来降低特定基因表达的方法。siRNA与目标mRNA序列特异性结合,导致mRNA被切割和降解,从而减少相应蛋白的产生。 - 这是一种“转录后沉默”方法,因为它在mRNA水平上阻止基因表达,而不改变DNA序列本身。 - siRNA沉默通常是临时的,只在siRNA存在时有效。 - CRISPR+guideRNA: CRI

Virulence Plasmid Absence in Y. enterocolitica 1Aa Subcluster

Author: gene_x

Abstract: [![ggtree_and_gheatmap_198](/static/Yersiniomics/ggtree_and_gheatmap_198.png "ggtree_and_gheatmap_198")](/static/Yersiniomics/ggtree_and_gheatmap_198.png "ggtree_and_gheatmap_198") >Pathogenicity of

Preparing a GTF file from GenBank for bacterial RNA-seq analysis, using the example of WA

Author: gene_x

Abstract: Preparing a GTF file from GenBank for bacterial RNA-seq analysis, using the example of WA 1. In the example Yersinia enterocolitica strain WA #[IMPORTANT FINAL STEPS] [STEP1] genbank

Differences Between Molecular and Genomic Biomarkers

Author: gene_x

Abstract: The terms "molecular biomarker" and "genomic biomarker" refer to specific types of biomarkers used in the field of biomedicine for diagnosis, prognosis, and monitoring the response to treatment, among

BCR (B-cell receptor) and TCR (T-cell receptor) sequencing

Author: gene_x

Abstract: BCR (B-cell receptor) sequencing and TCR (T-cell receptor) sequencing are molecular techniques used to analyze the genetic diversity of B-cell and T-cell receptors within an immune response. These rec


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